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Differentially Private Stochastic Gradient Descent (DP-SGD) has become a widely used technique for safeguarding sensitive information in deep learning applications. Unfortunately, DP-SGD’s per-sample gradient clipping and uniform noise addition during training can significantly degrade model utility and fairness. We observe that the latest DP-SGD-Global-Adapt’s average gradient norm is the same throughout the training. Even when it is integrated with the existing linear decay noise multiplier, it has little or no advantage. Moreover, we notice that its upper clipping threshold increases exponentially towards the end of training, potentially impacting the model’s convergence. Other algorithms, DP-PSAC, Auto-S, DP-SGD-Global, and DP-F, have utility and fairness that are similar to or worse than DP-SGD, as demonstrated in experiments. To overcome these problems and improve utility and fairness, we developed the DP-SGD-Global-Adapt-V2-S. It has a step-decay noise multiplier and an upper clipping threshold that is also decayed step-wise. DP-SGD-Global-Adapt-V2-S with a privacy budget of 1 improves accuracy by 0.9795%, 0.6786%, and 4.0130% in MNIST, CIFAR10, and CIFAR100, respectively. It also reduces the privacy cost gap by 89.8332% and 60.5541% in unbalanced MNIST and Thinwall datasets, respectively. Finally, we develop mathematical expressions to compute the privacy budget using truncated concentrated differential privacy (tCDP) for DP-SGD-Global-Adapt-V2-T and DP-SGD-Global-Adapt-V2-S. 

Abstract Background Blood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin infusion systems. In recent years, deep learning techniques have been utilized for a more accurate BG level prediction system. However, continuous glucose monitoring (CGM) readings are susceptible to sensor errors. As a result, inaccurate CGM readings would affect BG prediction and make it unreliable, even if the most optimal machine learning model is used. Methods In this work, we propose a novel approach to predicting blood glucose level with a stacked Long short-term memory (LSTM) based deep recurrent neural network (RNN) model considering sensor fault. We use the Kalman smoothing technique for the correction of the inaccurate CGM readings due to sensor error. Results For the OhioT1DM (2018) dataset, containing eight weeks’ data from six different patients, we achieve an average RMSE of 6.45 and 17.24 mg/dl for 30 min and 60 min of prediction horizon (PH), respectively. Conclusions To the best of our knowledge, this is the leading average prediction accuracy for the ohioT1DM dataset. Different physiological information, e.g., Kalman smoothed CGM data, carbohydrates from the meal, bolus insulin, and cumulative step counts in a fixed time interval, are crafted to represent meaningful features used as input to the model. The goal of our approach is to lower the difference between the predicted CGM values and the fingerstick blood glucose readings—the ground truth. Our results indicate that the proposed approach is feasible for more reliable BG forecasting that might improve the performance of the artificial pancreas and insulin infusion system for T1D diabetes management.